Since 2016, the ABCD Charitable Trust has supported the Laboratory of Genetic Neurobiology, a research unit headed by psychiatrist, professor and researcher Russell L. Margolis, affiliated with the Division of Neurobiology of the Department of Psychiatry at Johns Hopkins University School of Medicine in the United States.The ABCD Trust partially funds the innovative research strategy of the Margolis team, exploring some of the most difficult questions posed by schizophrenia and other psychiatric diseases. As specific objectives, the laboratory’s work aims in the short term to discover mechanisms that can lead to neurological diseases and to develop treatment strategies for diseases caused by the mutation of a single gene studied by the group in the medium-term. Its long-range goal is to apply learnings from studying these relatively simpler diseases to more complicated disorders, such as schizophrenia. At the same time, the laboratory called on support from the ABCD Trust to advance its research on improving care to persons with schizophrenia and schizoaffective disorder, as well to better understand these diseases for development of more effective interventions.
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A leader in robotic surgery, the Brady Urological Institute, affiliated with the Johns Hopkins University School of Medicine (JHU) in the United States, develops a pilot training and teaching program in the area. The work is overseen by Dr. Mohamad Ezzeddine Allaf, head of Urology at Johns Hopkins Hospital and professor at JHU. The ABCD Charitable Trust funds two scholarships in term of its support.
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Leveraging its relationship with researchers from both the Departments of Psychiatry of the Federal University of São Paulo (Unifesp) and Johns Hopkins University (JHU), the ABCD Charitable Trust has fostered collaboration between the two institutions. With this, it allowed the teams of researchers Jair Mari, Rodrigo Bressan and Ary Gadelha (Unifesp) to work with the Genetic Neurobiology Lab, JHU. Among the actions developed: presentations by researcher Russell L. Margolis (JHU) at the Schizophrenia Program Symposium 2017 of the Schizophrenia Program (PROESQ) and in the grand rounds of the Department of Psychiatry of Unifesp, in 2019; Bressan and Gadelha’s visit to JHU in 2019; one-month experience by residents Felipe Arcadepani and Bianca Camerini (Unifesp) at JHU; bressan and Gadelha presentation at the Psychiatric Research Seminar in 2021 at JHU; and presentation of the researcher Frederick Nucifora Jr. (JHU) at the webinar “Subtyping schizophrenia as an approach to precision medicine in psychiatry”, in 2021, and at the PROESQ Symposium in 2022.
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